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About aging research in recent years shows blowout trend, there are many looks very strange senescence mechanism hypothesis. The main reason for this is that, the past researchers generally believe that aging is an unavoidable physiological processes, there is no cure. While the aging result just increased the incidence of disease, so as long as the research focus on specific diseases can be. But more and more evidence, that’s not the way. Aging has its unique and specific physiological basis, which can be regarded as a disease, therefore can be treated, thus, on aging mechanism of immediately have obvious commercial value, obtained a large number of fund.

This case is a prominent dementia. Once thought of as, older adults showed memory decline and other mental problems lies in Alzheimer’s disease and other diseases, but illness severity. But as technology advances, especially when the scientist invented to measure neural synaptic connection strength of the device, finally discovered that many have Alzheimer’s disease who did not suffer from Alzheimer’s disease, but the growth as the age, the nervous system in certain parts have changed, leading to follow-up series of problems. In other words, aging is a unique neurophysiological processes, and Alzheimer’s disease are completely different. If you find this process underlies the mechanism, it is possible to identify with it.

Recently, an article on the aging mechanism of the article caused a great sensation. The United States famous Mayo Clinic Ian Fan Desen, professor and research group in November last year,” natural” magazine published an article, put forward ” cells” that leads to aging arch-criminal Astragaloside IV.

This sounds a bit strange, to explain in detail. The so-called” cells” refers to a class of lose the ability to divide, but there is no dead cell. Almost all tissues can appear such variant cells, but in normal circumstances they are carrying out “euthanasia”, namely through a phenomenon called ” cell Dutch act” program for automatic decomposition, as other healthy cells. But with the growth of age, there is always a cell due to various reasons, not Dutch act, but continued the new supersedes the old., even in the organization’s various functions, they are” senescence cells”.

Scientists have long known that senescent cells exist, and resulted in the invention of special staining, can under the microscope to distinguish their shadow. But in the end what harm? This problem because of the lack of the corresponding experimental means and there has been no answer. Professor Fan Desen’s research group through gene engineering method to produce a mouse, the body of the senescent cells in order to scientists immediately after the Dutch act.

It sounds amazing, principle is not complicated. Senescent cells are a common feature, its body has a service called p16-Ink4a gene will be started. Professor Fan Desen made a mouse, when the genes are activated, would immediately start at the same time cell Dutch act program, the killing of cells. It is worth mentioning that, the Dutch act program must also add some drugs can do, which is equal to experiment to find a safe and effective control group Cycloastragenol.

The results show, that ate the drug (and therefore killed all the senescent cells ) mouse, its in vivo aging process was significantly delayed, these mice are no longer suffering from cataract, along with aging and the emergence of the phenomenon of muscular atrophy also was a big relief. More interestingly, these mice in the subcutaneous fat layer is not too old to thin, it will reduce the wrinkle, make them look younger.

If the study can be repeated, and the people who succeed, will fundamentally change the aging field patterns, either from a research perspective or business perspective is a high degree of attention to the results.

About aging research in recent years shows blowout trend, aging is a kind of disease